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Yu-Wen Zhang Selected Research

6- (6- (1- methyl- 1H- pyrazol- 4- yl)- (1,2,4)triazolo(4,3- b)pyridazin- 3- ylsulfanyl)quinoline

8/2013Strengthening context-dependent anticancer effects on non-small cell lung carcinoma by inhibition of both MET and EGFR.
9/2010MET kinase inhibitor SGX523 synergizes with epidermal growth factor receptor inhibitor erlotinib in a hepatocyte growth factor-dependent fashion to suppress carcinoma growth.

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Yu-Wen Zhang Research Topics

Disease

18Neoplasms (Cancer)
01/2020 - 01/2002
4Neoplasm Metastasis (Metastasis)
01/2017 - 01/2002
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 08/2013
2Infections
01/2021 - 11/2004
2Osteoarthritis
02/2014 - 08/2005
2Osteophyte
02/2014 - 08/2005
2Melanoma (Melanoma, Malignant)
01/2012 - 01/2005
2Carcinoma (Carcinomatosis)
09/2010 - 01/2005
2Sarcoma (Soft Tissue Sarcoma)
10/2009 - 11/2004
2Leiomyosarcoma
10/2009 - 01/2005
2Glioblastoma (Glioblastoma Multiforme)
01/2005 - 11/2004
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2021
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
04/2020
1Aneuploidy (Aneuploid)
01/2020
1Experimental Arthritis
01/2020
1Rheumatoid Arthritis
01/2020
1Poisoning
07/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2019
1Hyperglycemia
01/2019
1Hypertension (High Blood Pressure)
01/2019
1Idiopathic Hypogonadotropic Hypogonadism
01/2019
1Dyslipidemias (Dyslipidemia)
01/2019
1Brain Neoplasms (Brain Tumor)
01/2019
1Abdominal Obesity
01/2019
1Xeroderma Pigmentosum (Kaposi's Disease)
01/2018
1Thymic epithelial tumor
10/2017
1Thymoma (Thymic Carcinoma)
01/2016
1Hematologic Neoplasms (Hematological Malignancy)
10/2015
1Arthritis (Polyarthritis)
03/2014
1Lung Neoplasms (Lung Cancer)
01/2012
1Uterine Diseases (Endometrial Disease)
05/2009
1Adenocarcinoma
05/2009
1Congenital Abnormalities (Deformity)
08/2005
1Joint Diseases (Joint Disease)
08/2005
1Prostatic Neoplasms (Prostate Cancer)
11/2004
1Stomach Neoplasms (Stomach Cancer)
11/2004
1Renal Cell Carcinoma (Grawitz Tumor)
01/2002
1Carcinogenesis
01/2002

Drug/Important Bio-Agent (IBA)

6Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
08/2013 - 10/2003
5LigandsIBA
09/2010 - 01/2002
4Proteins (Proteins, Gene)FDA Link
04/2020 - 03/2014
4Phosphotransferases (Kinase)IBA
01/2019 - 09/2010
4ErbB Receptors (EGF Receptor)IBA
03/2014 - 09/2010
3MitogensIBA
02/2014 - 08/2005
2paeoniflorin-6'-O-benzenesulfonateIBA
01/2020 - 01/2020
2Pharmaceutical PreparationsIBA
01/2019 - 09/2010
2DNA (Deoxyribonucleic Acid)IBA
01/2018 - 01/2012
2tyrosine receptor (receptor, tyrosine)IBA
05/2015 - 08/2013
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
08/2013 - 01/2005
2Erlotinib Hydrochloride (CP 358,774)FDA Link
08/2013 - 09/2010
26- (6- (1- methyl- 1H- pyrazol- 4- yl)- (1,2,4)triazolo(4,3- b)pyridazin- 3- ylsulfanyl)quinolineIBA
08/2013 - 09/2010
1Immunoglobulin G (IgG)IBA
01/2021
1PlatinumIBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2020
1peoniflorinIBA
01/2020
1Biological ProductsIBA
01/2020
1EstersIBA
01/2020
1Immune Checkpoint InhibitorsIBA
01/2020
1Antitubercular AgentsIBA
07/2019
1SodiumIBA
07/2019
1Aminosalicylic Acid (Rezipas)FDA Link
07/2019
1Vitamin DFDA LinkGeneric
01/2019
1Testosterone (Sustanon)FDA Link
01/2019
1Cisplatin (Platino)FDA LinkGeneric
01/2019
1OsteocalcinIBA
01/2019
1Diethylnitrosamine (N-Nitrosodiethylamine)IBA
01/2018
1Dasatinib (BMS 354825)FDA Link
01/2018
1trametinibIBA
01/2018
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018
1src-Family KinasesIBA
01/2018
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
10/2017
1selinexorIBA
10/2017
1Exportin 1 ProteinIBA
10/2017
1Transcription Factors (Transcription Factor)IBA
10/2017
1Therapeutic UsesIBA
10/2017
1MK 2206IBA
01/2017
1Anaplastic Lymphoma KinaseIBA
05/2016
1Biomarkers (Surrogate Marker)IBA
01/2016
1Karyopherins (Importin)IBA
10/2015
1Methylnitronitrosoguanidine (MNNG)IBA
05/2015
1onartuzumabIBA
08/2013
1LuciferasesIBA
01/2012
1MethyltransferasesIBA
01/2012
1Histones (Histone)IBA
01/2012
1Histone Deacetylases (Histone Deacetylase)IBA
01/2012
1theasinensin AIBA
01/2012
1Histone Deacetylase InhibitorsIBA
01/2012
1DecitabineFDA Link
01/2012
1trichostatin A (A 300)IBA
01/2012
1Neutralizing AntibodiesIBA
10/2009
1rilotumumabIBA
10/2009
1Hormones (Hormone)IBA
05/2009
1Fumigant 93 (D-D)IBA
05/2009
1SteroidsIBA
05/2009
1Small Interfering RNA (siRNA)IBA
11/2004
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
11/2004
1Thrombospondin 1IBA
10/2003
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2003

Therapy/Procedure

4Therapeutics
05/2015 - 07/2004
2Drug Therapy (Chemotherapy)
01/2021 - 01/2019